3

Effect of HJ11 on locomotor activity and anxiety in the open field test (OFT). Data represent the mean ± standard error of the mean (SEM). *p < 0.05 versus the sham. ^†p < 0.01 versus the sham. ^‡p < 0.05 versus CIS + DW. ^§p < 0.01 versus CIS + DW. CIS = chronic immobilization stress; DW = distilled water; HJ11 = Liver Qi Depression pharmacopuncture.