Figure 3
From: Acupuncture Points and Their Relationship with Multireceptive Fields of Neurons
Peripheral and central sensitization in the afferent visceral nerves and spinal cord. Wide dynamic range (WDR) neurons (green) activated by visceral inflammation at the intestine level. Inflammatory mediators are released through immune, epithelial, neuronal and glial cells. ATP = adenosine triphosphate; CGRP = galcitinin gene related peptide; DRG = dorsal root ganglion; 5-HT = 5-hydroxytryptamine; H+ = hydrogen ions; NO = nitric oxide; SP = substance P.