Differential Effect of Electroacupuncture on Inflammatory Adipokines in Two Rat Models of Obesity

Table 3 Measured outcomes in blood sera on Day 12.*^,^†

Outcome	Obese Zucker		Obese Long Evans		p for overall difference	p for interaction
	Group 1 EA	Group 2	Group 3 EA	Group 4
Adiponectin (mg/mL)	15.28 (6.82)^a	21.72 (2.55)^ab	25.99 (3.68)^c	22.74 (2.07)^bc	0.035	0.024
Leptin (ng/mL)	66.16 (8.72)^a	63.23 (4.93)^a	5.62 (1.71)	3.85 (0.72)	<0.001	0.814
Adiponectin:leptin (×10³)	0.24 (0.13)^a	0.33 (0.03)^a	4.72 (1.00)	6.01 (0.82)	<0.001	0.038
IL-10 (pg/mL)	12.91 (5.10)^a	20.15 (7.57)^ab	27.86 (8.32)^b	23.90 (10.96)^ab	0.082	0.167
TNF-α (pg/mL)	3.46 (1.78)^a	18.89 (1.48)	3.43 (1.44)^a	3.26 (1.15)^a	<0.001	<0.001
IL-10:TNF-α	2.66 (0.93)	1.00 (0.49)	9.01 (3.79)^a	6.93 (2.18)^a	<0.001	0.821
Insulin (ng/mL)	13.63 (1.91)^b	12.42 (3.24)^b	3.13 (1.31)^a	2.87 (1.02)^a	<0.001	0.628

Data presented as mean (standard deviation).
* A regression model was used to allow modeling a two-way factorial design with interaction. Where there was evidence that model assumptions were not satisfied, robust standard errors were used. Stata 13.1 was used for all analyses with two-sided p < 0.05 considered statistically significant in each case.
^† Stata lettering system identifies which particular pairs of groups are different, so columns sharing a letter showed no evidence of being different and columns not sharing a letter (including columns where both are “blank”) showed evidence of being different; “blanks” are different to all other values including other “blanks.”
EA = electroacupuncture; IL = interleukin; TNF = tumor necrosis factor.

ISSN: 3059-4049