Does Acupuncture Alter Pain-related Functional Connectivity of the Central Nervous System? A Systematic Review

Table 3 Reported brain areas in patients after short-term acupuncture intervention.

Study	BIT	Diagnosis	Areas activated/deactivated	Reported reduction of pain
Maeda et al [26]	fMRI	CTS	IC, IFG, ITG, MFG, OCG, PFC, PMC, pSMA, S1, S2, SMG, STG, Th	Yes
Napadow et al [30]	fMRI	CTS	ACC, Amyg, CC, DLPFC, Hyp, IC, MPFC, S1, Th	Not reported
Pariente et al [31]	PET	1^st MO	ACC, DLPFC, IC, midbrain	No
Harris et al [27]	PET	FM	ACC, Amyg, CAU, CC, IC, NAC, Th	No

The bold font indicates activation to acupuncture; italic font indicates deactivation to acupuncture.
ACC = anterior cingulate; Amyg = amygdala; CAU = caudate; CC = cingulate cortex; DLPFC = dorsolateral prefrontal cortex; Hyp = hypothalamus; IC = insular cortex; IFG-inferior frontal gyrus; ITG = inferior temporal gyrus; MFG = middle frontal gyrus; MPFC = medial prefrontal cortex; NAC = nucleus accumbens; OCG = occipital gyrus; PFC = prefrontal cortex; PMC = premotor cortex; pSMA = presupplementary motor area; S1 = primary somatosensory cortex; S2 = secondary somatosensory cortex; SMG = supramarginal gyrus; STG = superior temporal gyrus; Th = thalamus.

ISSN: 3059-4049